Authors reviewed and analyzed sixty-eight patients with breast cancer who treated with the primary combination chemotherapy throughout three cycles of FAC regimen pre and postoperatively between January, 1990 and April, 1992. Thirty-eight
patients
of
reviewed cases performed the quadrantectomy and axillary node dissection with adjuvant chemotherapy and/or radiotherapy or hormonal therapy.
@ES The results were obtained as follows:
@EN 1) of 68 cases who performed the preoperative inductive combination chemotherapy, 38 cases (55%) were performed by quadrantectomy and 26 cases(68%) of the quadrantectomy group revealed to TNM stage IIa or less.
2) Age distribution was most frequent in the 6th decade(39%)
3) The primary tumor size after preoperative inductive chemotherapy was less than 5cm. In largest diameter in all of quadrantectomy group.
4) The site of the primary tumor mass in quadrantectomy group was revealed to 16 cases in right breast and 22 cases in left breast, and outer upper quadrant of the breasts was involved in 29 cases(76%) o f38 cases, most commonly.
5) The breast skin incision in quadrantectomy group was performed with radial and curvilinear skin incisions in 19 cases, respectively, and the axillary incision was performed with separated manner in 23 cases.
6) On the histopathologic findings in quadrantectomy group, invasive ductal carcinoma was 32 cases(98%), most commonly.
7) Involovement of the axillary lymph node was not found in 30 cases(53%) of quadrantectomy group.
8) The postoperative complications in quadrantectomy group occured in 7 cases(19%).
9) In postoperative adjuvant treatments, combination chemotherapy was performed in all cases of quadrantectomy group, and chemoradiotherapy was 9 cases and chemoradiotherapy with hormonal therapy was 5 cases.
In conclusion, the quadrantectomy and axillary node dissection offer an effective alternative therapy to mastectomy for patients with breast cancer, and in future, authors would propose the further study and its results for the outcome.
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